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022824 - Fred Hutch to lead new federal Cancer Screening Research Network
ALERT: BE CAUTIOUS This email originated outside the organization. Do not open attachments or click on links if you are not expecting them. New clinical trials consortium | Reducing your risk of cancer | Rare cancer research effort View as Web page <https://secure.fredhutch.org/site/R?i=njF6AbqxLmHno6np3MglQWEzeXP4ketQ3-fQ2k2rxySRYJNmBLJnvg> <https://secure.fredhutch.org/site/R?i=LXQb8oNolmD8EgoZkSkbhmSWkBO2btT2CSYQt3pLUuY7VwRz0WXS7g> <https://secure.fredhutch.org/images/content/pagebuilder/fhcc-eml-hdr-shadow.png> <https://secure.fredhutch.org/images/content/pagebuilder/hdr-eml-hutch-news-fhcc.jpg> February 28, 2024 ⋅ A monthly digest of the latest from Fred Hutch Clinical trials will evaluate emerging technologies that screen for cancer <https://secure.fredhutch.org/site/R?i=UBjUaCKxHfraZKJS41tmkJMw94NYx0I71rdzzR1Fjro-v0FV2UKRnw> Fred Hutchinson Cancer Center is at the helm of a new clinical trials consortium, the Cancer Screening Research Network, or CSRN, created by the National Cancer Institute, part of the National Institutes of Health, to advance President Joe Biden’s Cancer Moonshot by improving early detection of cancers. The CSRN will play a primary role in moving the Moonshot closer to its goals, which include slashing the age-adjusted death rate from cancer by at least half. The primary focus will be on diagnosing cancer sooner and reducing health inequities — and preventing cancer in the first place — by evaluating new and complex technologies that screen for cancer. Screening for cancer is a key part of prevention because when more cancers are detected before people develop symptoms, it is expected that treatment — perhaps less aggressive treatment — can lead to better outcomes. Fred Hutch will lead the CSRN’s Coordinating and Communication Center (CCC) and the Statistics and Data Management Center (SDMC) that will oversee cancer screening clinical trials enrolling diverse participants. The initial studies will examine Multi-Cancer Detection assays (MCDs), which look for byproducts of cancer cells in blood or other bodily fluids that could indicate early-stage cancer. Although these tests are being commercially marketed as effective cancer screening tools, they are so new that there is no research showing they actually work to reduce deaths from cancer. The U.S. Food and Drug Administration has not authorized any MCD tests. But, if research shows that these new blood tests are successful at detecting cancer early and preventing cancer-related deaths, it could help reshape the cancer landscape. Any positive results would need to be confirmed by further testing. The new network will help to keep patients well-informed about these emerging detection tools <https://secure.fredhutch.org/site/R?i=QFjcuoMy1Usyqt7wWiDwwIatLvIvN1zc6IYq_Pla8ETEDkqfb0M4ZQ> . ________________________________ Reducing your risk of cancer <https://secure.fredhutch.org/site/R?i=L1Ko_PKKuhcHuy5oc0Qk0T0zhRhifGTZnUsfp_BmcuaZ1_pBQg33kA> Illustration by Stephanie Liszewski / Fred Hutch News Service. Confused about when to get screened for what? Wondering what matters most for long-term good health? Fred Hutch experts break down the basics in this handy decade-by-decade guide <https://secure.fred hutch.org/site/R?i=emNadWvnulOPVAHuJNX7cw-P3XIeU4YVoFcB6VlOwCPd9i-8RO1fgw> for recommended screenings and other preventive actions. ________________________________ The Latest Fred Hutch launches rare cancer research effort <https://secure.fredhutch.org/site/R?i=kQWwkEzK_xeDALq9yNE_68HI3dSqVCRDy6fX6Izq4joqsPJEgOAmIg> A new initiative led by Fred Hutch’s Taran Gujral, PhD, aims to accelerate advances with a drug-matching platform that uses artificial intelligence to help researchers, clinicians and, most importantly, patients find additional uses for drugs that have already gone through clinical trials and received approval. New biomarker could guide skin tumor treatment <https://secure.fredhutch.org/site/R?i=IAu8fxZ4_PBBLUndi5ISF4fL1sHCAyPJAsF3TcAViQOkJsd2Gm8lNA> New work from two teams of scientists at Fred Hutch and the University of Washington School of Medicine showed that the frequency of circulating battle-ready anti-cancer immune cells can act as a biomarker in patients with an aggressive skin tumor: Merkel cell carcinoma patients with higher levels in their blood are more likely to respond to immune checkpoint inhibitors, or ICIs. The findings are a step toward the development of a clinical test that could someday guide MCC treatment. Boosting the effectiveness of CAR T-cell therapies <https://secure.fredhutch.org/site/R?i=7Nw2SMm0IKLt72fIyqsOUCp2sHHZCgva-UhA5iRiQBzHY7MNfqZo1g> Erik Kimble, MD, wins award from the American Society of Gene & Cell Therapy for his work on understanding how immunotherapy can be trained to attack hematologic malignancies, especially acute myeloid leukemia. ________________________________ Donate Your Vehicle! Your old car, motorcycle, boat or RV can help fuel innovative research. Donating your vehicle to Fred Hutch is easy, plus we’ll tow it at no cost. <https://secure.fredhutch.org/site/R?i=JJsCs-YNWzPFSBxPT2JJcnBw2QkMQUfWPQG8ZgDzjPEe6qYOWlXlcw> ________________________________ Share this newsletter with family or friends <https://secure.fredhutch.org/site/R?i=lW10S3OnOf2w79bKiO9aMGggQyaCdRpZgAglivQO18VBWek59y2Mpg> <https://secure.fredhutch.org/site/R?i=A4Aq99iLl_RWJzi6SaINgJ8NxirUwPs4fUN9QCEFxxOLQZuyvmgXrg> 1100 Fairview Ave. N., Seattle, WA 98109 communications@fredhutch.org <mailto:communications@fredhutch.org> 206.667.5000 <https://secure.fredhutch.org/site/R?i=XjHCGqg5kvwmUdfPVe9ZYzkNu5bTKwMZ1_4nr64_jeCT9RtOBioSFA> <https://secure.fredhutch.org/site/R?i=fbSENFZAKZpL_EA00ZZbEzg48Wla3GnurOF8IgR29EOmKdRLnhPRwA> <https://secure.fredhutch.org/site/R?i=SJ8GPtyZqiYlOkFK5fCNjCurJyKGlxloo6A1gvDfolirGpd_5dKkig> <https://secure.fredhutch.org/site/R?i=97rmXiH_kfsVdNvnDhg-3gnhuFogb0BSNzEySKXIlWb7ImSiP7X-dg> ________________________________ Fred Hutchinson Cancer Center is a 501(c)(3) nonprofit organization. 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