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042424 - New weight-loss drugs and cancer
ALERT: BE CAUTIOUS This email originated outside the organization. Do not open attachments or click on links if you are not expecting them. Semaglutides and cancer | Alcohol, cannabis use after diagnosis | Clinical trial participation View as Web page <https://secure.fredhutch.org/site/R?i=CuyBYsR4NB-LMc0Zs4yrNShS9bBPBs6uypTL8pu9d-4Znv-wkbjoxw> <https://secure.fredhutch.org/site/R?i=AQDeUGihyABD-GcdlQMv8_aujgIFozvQedFQx1vNbIAstU1KAVn_2w> <https://secure.fredhutch.org/images/content/pagebuilder/fhcc-eml-hdr-shadow.png> <https://secure.fredhutch.org/images/content/pagebuilder/hdr-eml-hutch-news-fhcc.jpg> April 24, 2024 ⋅ A monthly digest of the latest from Fred Hutch What cancer patients and doctors need to know about new weight loss drugs <https://secure.fredhutch.org/site/R?i=W_v744q2d-sw3lm0tAUpxE9Vti9BqOUkxzhLxIyRd-fTK9jehfJZBw> Much has been discussed about the bumper crop of weight-loss drugs approved in the U.S. over the last several years. Obesity drives a number of different cancers, so it makes sense that both patients dealing with cancer — and the clinicians and researchers trying to kick it to the curb — are curious whether weight-loss drugs have a role in cancer prevention. Shedding extra pounds could help patients cut back on their risk for not just cancer recurrence, but also diabetes, cardiovascular disease and other conditions driven by excess weight and the inflammation it causes. But there is much to consider when it comes to using the new semaglutide drugs — and that’s not even factoring in the stiff price and daunting side effects. What’s the lowdown for those dealing with cancer <https://secure.fredhutch.org/site/R?i=fgZy3cPZmZaOvTtaqpzHwH5r0lYo5iqiJqZ8DsozaBXkqulQggRAlQ> ? Are these new drugs a boon, a bust or just a big old can of worms? We talked to a host of stakeholders in the cancer community — patients, clinicians, psychologists, researchers, dietitians and more — to help you navigate the latest wave in the weight-loss world. ________________________________ Smarter science summers <https://secure.fredhutch.org/site/R?i=FRp2Oi7A_r8iyYyrptXX4EBMi2iUA71HFG5F-3ZV8DSztTHxwjRrJg> Photo courtesy of Caren Brinkema Our education programs span the biomedical disciplines and research interests pursued at Fred Hutch — from basic, human biological, clinical and public health sciences research to a range of cancers and infectious diseases — with a commitment to increasing access and creating pathways for those trainees historically excluded. Learn more <https://secure.fredhutch.org/site/R?i=nM h8IKBl4pEUYSt5cxrcB-dc6wg5fSbiS9f6KdpIKx4NWPtia7wRqw> . ________________________________ The Latest Alcohol, cannabis use after cancer: ‘eye-opening’ <https://secure.fredhutch.org/site/R?i=V7ndgo2hfg-kMvGaxpXdgTxxSj03Klc97_jeEPikvVXqlXzvtupWZg> Public health scientists at Fred Hutch dug into cannabis and alcohol use among their cancer patients with two recent studies. Results from one were surprising: More than 40% of the patients reported cannabis use after their cancer diagnosis, according to lead author Mimi (Trucmai) Ton, MPH. Updates on clinical trials and cancer patients <https://secure.fredhutch.org/site/R?i=SgWUj6BkQxDpD2obHM2bhgpIlW7AmSEGcubE-PGHbEPsUlaum6R5_A> When participation in all types of cancer research studies are considered, at least one in five people with cancer in the U.S. (nearly 22%) participate in some form of clinical research, according to research by Joe Unger, PhD, MS. The Fred Hutch researcher also led a study that found clinical trials have started to modify eligibility criteria to be more inclusive of patients with brain metastasis. Amyloidosis patient participates in trial that also helps her family <https://secure.fredhutch.org/site/R?i=V1U1DpY7U73qEY-nZvz7L-hhbyIgvnkFKWgAJ7zeX3A4ad-dLxFvJA> When Sally Cox was diagnosed with light chain amyloidosis (AL), she was shocked for many reasons, including that there were no FDA-approved treatments. So, she agreed to participate in a clinical trial that addressed her disease — and ended up helping her sister-in-law. New approach, tools reveal hidden lung cancer subtypes <https://secure.fredhutch.org/site/R?i=oZYgATJsL8CBPtRFU8KoqS54yaCA2-lNBr7Z5ZqhkREcrpNm6-E9mA> Big-picture patterns of DNA packaging, gene activation and mutations could hold the information needed to develop a blood-based biopsy for small cell lung cancer patients, according to new work published by scientists at Fred Hutch. AACR 2024: Liquid biopsies, better treatments <https://secure.fredhutch.org/site/R?i=ACR5QRTNWhDl-5RWep-H7N-QNWPJL2I6ITOuYMds9Dliz8e43E1MWg> Liquid biopsies, artificial intelligence and cancer vaccines were just a few of the key topics at the 2024 meeting of the American Association of Cancer Research, or AACR, held earlier this month. Baseball, part of Fred Hutch’s history, was on the agenda as immunologist Phil Greenberg, MD, threw out the first pitch at a San Diego Padres game. Colorectal cancer risk and red meat <https://secure.fredhutch.org/site/R?i=OS060lfbZW977RXPVaZwuVNV_yLAdx9WazE_SO-c4XSwuRzdVnMqiA> New research from a Fred Hutch collaboration with USC Norris Comprehensive Cancer Center and published in March quantifies the risk posed by eating red or processed meat. The collaboration also found two genetic mutations that, for those carrying them, make eating red and processed meat even more hazardous. ________________________________ Good News Ovarian cancer research gets funding boost <https://secure.fredhutch.org/site/R?i=I48wGPphjFWWsXl1vEyjqICs-w6JEfJsK617bX37coXbjtM0t6qALQ> Fred Hutch and UW Medicine researchers Holly Harris, MPH, ScD, and Elizabeth Swisher, MD, each received $200,000 from Seattle’s Rivkin Center and Washington state’s Andy Hill Cancer Research Endowment (CARE) Fund for new work to identify risk factors and promote better prevention for often-intractable ovarian cancers. Dr. Karen Peterson receives distinguished service award <https://secure.fredhutch.org/site/R?i=SYgJ1qkVxI6UGbDHohlyp8bcRlI44Li8cErIBXhw7xhpJBRSZU4b7w> Karen Peterson, PhD, the director of the Office of Scientific Career Development at Fred Hutch, has supported the career and professional development of postdoctoral researchers for nearly 25 years. She recently received the National Postdoctoral Association Distinguished Service Award in recognition of her profound, sustained contributions to improving the postdoctoral experience. ________________________________ Help Cure Cancer Faster Fred Hutch Obliteride is a bike ride and 5K walk/run that empowers people to help cure cancer faster by raising funds to advance prevention, detection, treatment and cures. Our $5 early-bird pricing ends May 9! <https://secure.fredhutch.org/site/R?i=JSxiHDLkQ3zN6OPkhBS7kKI-aYRu4B5QMgsd5viw0Q__vP_-h4CcKA> ________________________________ Share this newsletter with family or friends <https://secure.fredhutch.org/site/R?i=BmzXCb5aysv_VRAjhIUaWOnlzSyJ343S1GXTFTNbcZj9ca698OkF2g> <https://secure.fredhutch.org/site/R?i=-roLQ4LSPK0Lbm3tGj_lKRlwRcCrxA_eo6HLyC8m1WR6h80n9TLgWg> 1100 Fairview Ave. N., Seattle, WA 98109 communications@fredhutch.org <mailto:communications@fredhutch.org> 206.667.5000 <https://secure.fredhutch.org/site/R?i=nDVzZF2EJu595zxthGJAGk-_iXX9bD0woUovHT44Pg84BaY7NIJtBQ> <https://secure.fredhutch.org/site/R?i=NaV0ne-R2k2czp4ZJ9QJGuGtR-XPrWiqdo4Iwf82zPpGhM8Cwui2fg> <https://secure.fredhutch.org/site/R?i=SgV3w6Xkrxi4WC4e1AAH4-6z6PhSMy-txgHrB-MqxC-jw8LKY-cZEA> <https://secure.fredhutch.org/site/R?i=NSOJ324TmYswMCONgVsgPyltXXk97jVwIm94TTq2pzN6dXHiVHeXZA> ________________________________ Fred Hutchinson Cancer Center is a 501(c)(3) nonprofit organization. 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